Wii Play comes with a remote too I think ... one of the main reasons it sells so much these days.
I always heard about Super Mario Galaxy (epic platforming), Super Smash Bros. Brawl (epic fights, decent story), and Metriod Prime Corruption (epic graphics for Wii, good story). The Legend of Zelda: Twilight Princess is old ... but I heard good things about it too. Just got Mariokart Wii and with the wheel thing it's really hard to get used to at first, but pretty fun after a while - especially if you've played previous versions.
Totally forgot they had RE 4 for the Wii

gotta look into that.