If the right click on an item shows a 'destroy' option, it is probably a holiday event item and you can get all those back from Django in Draynor Market at any time.
If you have the key ring from 'One Small Favour' try all your keys to see which will go on it, drop any duplicates of keys on this ring.
If you have a POH with bookcases, most books will be found on there so can lose books.
Quite a few things seem to be things only needed for particular quests; if you have finished the quest get rid of the item (but maybe keep mourners clothes if you have not done all the Elven quests)
Have fun, my bank is always stuffed too
